HAV Immunogold Filtration Assay

HAV IgM Antibody Rapid Test

HAV Test Devices Background:

This HAV test is an immunogold filtration assay to detect the HAV IgM antibody in human serum samples. The HAV rapid test take about 2-4 munites to get the testing result, which makes it much easier to determine the immune status of individuals following exposure to HAV or to hepatitis A vaccine. Detection of anti-HAV antibodies in the absence of anti-HAV antibodies of type IgM, indicates either a previous infection with HAV or a successful vaccination. In general, a titer of 10 IU/L is considered to represent the minimal anti-HAV antibody concentration indicating immunization of the individual.

Immunogold Filtration Test Principle

Hepatitis A virus specific immunoglobulin M (IgM) antibody is a specific serological marker for early diagnosis of hepatitis A. This HAV immunogold test cassette is based on the dot immunogold combination assay (DIGFA) principle, which was developed since 1989, and is a new technique with the merit of simple and rapid immunological detection. With this HAV dot test cassette, we use the red colloidal gold particles to label the antibodies as indicator, and the millipore filtering membrane coated with antigen as the carrier. Affected by filtration speed and condensation of the HAV IgM antibody, the antigen-antibody reaction can happen rapidly.

When testing with this HAV cassette, add the serum sample to the Millipore membrane where HAAg is pre-coated, if there is HAV IgM antibody in the sample, the HAAg-anti-HAV IgM colloidal gold complex will emerge on the membrane as red dots which were visible to naked eyes. It takes about 2 to 4 minutes for the whole reaction to be carried out.

Introduction of Hepatitis A (HAV):

Hepatitis A is a strong infectious disease caused by HAV, it is spread generally having two means namely mouth and feces with strong infection characteristic. Hepatitis A is a prevalent disease in the human population, caused by the hepatitis A virus (HAV). Following a 14-40 day incubation period, HAV infection most commonly manifests itself by jaundice due to acute inflammation of the liver and subsequent elevated blood bilirubin concentrations.

This test is easy to use and the lest expertise is needed;
Takes 2-4 minutes to get the screening result;
No other reagent is needed;
Test results can be read visually without any instrument.

Catalog No.	Product Name	Package	Samples	Reading time	Storage Condition	Shelf Time
HAV 281	HAV Dot Test Cassette	1 Test/Pack, 25 Packs/Outer Box	Serum	Read results in 2-4 minutes	2-8℃	18 Months